BioMedica |

Case Report

| DOI: 10.51441/BioMedica/5-587

Diagnosis and Treatment of Adult-Onset Still’s Disease in a Female Patient - A Case Report with Review of the Literature

Authors: Yan Gao , Weiguo Jin , Qingsong Huang , Ailing Ma

Article Info

Authors

Yan Gao

Department of Pharmacy, Jiading District Hospital of Traditional Chinese Medicine, Shanghai, China

Weiguo Jin

Department of Pharmacy, Jiading District Hospital of Traditional Chinese Medicine, Shanghai, China

Qingsong Huang

Department of Internal Medicine, Jiading District Hospital of Traditional Chinese Medicine , Shanghai, China

Ailing Ma

Department of Internal Medicine, Jiading District Hospital of Traditional Chinese Medicine , Shanghai, China

Publication History

Received: December 31, 2021

Accepted:

Published:

Abstract

ABSTRACT Adult onset Still’s disease (AOSD), a rare autoinflammatory disorder, presents with many non-specific symptoms, such as rash leukocytosis, spiking fever and sore throat. Laboratory tests show high levels of C-reactive protein, ferritin and erythrocyte sedimentation rate reflecting the systemic inflammatory process. The patient was a middle-aged woman with high grade fever (39.8°C), sore throat, rash on limbs with pruritus, mainly at the joints (elbow, knee, and ankle), myalgias, poor appetite and arthralgia. Serum ferritin level was above 1500 (normal value: 14-233) ng/L. Anti-neutrophil and antinuclear antibodies and rheumatoid factors were negative. Combination of symptoms and ferritin levels led to the diagnosis of adult Still’s disease. She received a dose of methylprednisolone 40 mg twice a day, intravenously for one week with tapering to 40mg in the morning and 20mg in the evening in the second week and 40mg orally in the morning and 8mg in the evening for the next couple of weeks. After 15 days of initial treatment, fever and skin rashes subsided and other symptoms also gradually improved in further two weeks. This case highlights the importance of early diagnosis and timely treatment of adult Still’s disease to prevent potentially fatal complications.

Keywords: Adult-onset; Still’s disease; Female ; Ferritin ; Inflammatory disorder

Pubmed Style

Yan Gao, Weiguo Jin, Qingsong Huang, Ailing Ma. Diagnosis and Treatment of Adult-Onset Still’s Disease in a Female Patient - A Case Report with Review of the Literature. BioMedica. 1970; 01 (January 1970): -. doi:10.51441/BioMedica/5-587

Web Style

Yan Gao, Weiguo Jin, Qingsong Huang, Ailing Ma. Diagnosis and Treatment of Adult-Onset Still’s Disease in a Female Patient - A Case Report with Review of the Literature. https://biomedicapk.com/articles/online_first/587 [Access: April 19, 2024]. doi:10.51441/BioMedica/5-587

AMA (American Medical Association) Style

Vancouver/ICMJE Style

Yan Gao, Weiguo Jin, Qingsong Huang, Ailing Ma. Diagnosis and Treatment of Adult-Onset Still’s Disease in a Female Patient - A Case Report with Review of the Literature. BioMedica. (1970), [cited April 19, 2024]; 01 (January 1970): -. doi:10.51441/BioMedica/5-587

Harvard Style

Yan Gao, Weiguo Jin, Qingsong Huang, Ailing Ma (1970) Diagnosis and Treatment of Adult-Onset Still’s Disease in a Female Patient - A Case Report with Review of the Literature. BioMedica, 01 (January 1970): -. doi:10.51441/BioMedica/5-587

Chicago Style

Yan Gao, Weiguo Jin, Qingsong Huang, Ailing Ma. "Diagnosis and Treatment of Adult-Onset Still’s Disease in a Female Patient - A Case Report with Review of the Literature." 01 (1970), -. doi:10.51441/BioMedica/5-587

MLA (The Modern Language Association) Style

Yan Gao, Weiguo Jin, Qingsong Huang, Ailing Ma. "Diagnosis and Treatment of Adult-Onset Still’s Disease in a Female Patient - A Case Report with Review of the Literature." 01.January 1970 (1970), -. Print. doi:10.51441/BioMedica/5-587

APA (American Psychological Association) Style

Yan Gao, Weiguo Jin, Qingsong Huang, Ailing Ma (1970) Diagnosis and Treatment of Adult-Onset Still’s Disease in a Female Patient - A Case Report with Review of the Literature. , 01 (January 1970), -. doi:10.51441/BioMedica/5-587