The drive towards adopting modern ways of communication is nothing but a blessing in terms of quick, easy and valuable correspondence amongst professionals especially if they are working remotely. The provision of a group feature as a simple and instant messaging platform in WhatsApp is a highly popular channel for such communications. Unfortunately, a number of poor practices have also arisen which call for designing and implementing specific extrinsic and intrinsic communication-related policies for monitoring and balancing this social media correspndence hub available officially to most of the employees in an organization. Because of the lack of control and breach in the borderline between personal and professional life, an unclear, disjointed, and disconnected workplace communication is taking place. WhatsApp groups are thus hurting productivity more than these can help. Continue Reading

Oral Squamous Cell Carcinoma (OSCC) has become prevalent worldwide and is one of the leading cause of death. Derangement of anti-apoptotic proteins is important regarding OSCC development. Over-expression of these proteins lead to prolonged cellular survival, thus increasing the susceptibility of tumor formation. Commiphora wightii and molmol are the natural herbs with ability to down-regulate anti-apoptotic proteins by acting on Nuclear Factor-kappa B (NF-κB) pathway, p53 pathway, signal transducer and activator of transcription pathway, estrogen, cyclooxygenase 2 and mitogen activated protein kinase pathway. NF-κB pathway has been found to involve in the release of cytokine storm associated with COVID-19 disease. Commiphora wightii and molmol suppress the COVID-19 infection by their anti-inflammatory and anti-viral properties. This review sheds light on the effect of Commiphora wightii and molmol on suppression of oral cancer and COVID-19 infection by modulation of anti-apoptotic proteins and inflammatory pathway. Continue Reading

A very uncommon benign synovial membrane tumor is called lipoma arborescens. It often affects a single articulation, the knee. Despite a conventional imaging assessment, the lesion’s histological analysis is still required for the ultimate diagnosis. A 15-year-old boy attended the outpatient clinic of the Lahore General Hospital Lahore, Pakistan with pain and swelling in his left knee that had been steadily worsening over the previous 4 years. There were no concomitant prodromal symptoms, and the swelling was soft and non-tender while also inhibiting knee flexion. Soft tissue shadows were observed on radiographs. A large amount of subarticular erosion in the nearby tibial and femoral condyle was caused by the frond-like proliferation of fatty synovium, according to magnetic resonance imaging. Only the left knee joint showed focused areas of unusually elevated radionuclide uptake during the Technetium (Tc99m) bone scan. After an open synovectomy, the specimen underwent histological analysis, which revealed villiform... Continue Reading

Background and Objective: Mobile phones have become an indispensable part of our daily life. Nomophobia (NMP) is an abbreviation for “no-mobile-phone phobia,” which defines apprehension faced by mobile phone users in its absence which leads them to become technically unable to communicate. Objective of the study is to determine the prevalence of NMP and its association with the demographic factors among medical students of a private medical college in Lahore. Methods: A cross-sectional study was conducted among the medical students from first to final year classes from May to November 2021. A validated NMP questionnaire was used along with questions related to the sociodemographic profile and frequency of mobile phone usage by the respondents. The self-reported questionnaire was filled out by all the students who were present on the day of data collection. Data were analyzed by SPSS 20. Results: Out of 646 medical students, 618 filled the questionnaire. Out... Continue Reading

Background and Objective: The discrimination between benign and malignant adnexal masses is important for clinical management and surgical planning in such patients. The risk of malignancy index (RMI) is a combined parameter that is a simple, highly sensitive, and more specific scoring system based on three factors: serum cancer antigen 125 (CA-125) levels, ultrasonographic (USG) score, and menopausal status. The objective of the study is to evaluate the diagnostic efficacy of RMI for the primary evaluation of ovarian masses in females presenting at a local tertiary care hospital in Pakistan. Methods: This prospective observational study was carried out at the Gynecology outdoor clinic of Fouji Foundation Hospital, Rawalpindi, Pakistan. The study comprised 141 females admitted for surgical exploration of ovarian masses. Pre-operative USG evaluations of ovarian mass, menopausal status, and serum CA-125 levels were determined for all the patients. RMI was calculated and post-operative histopathology of resected ovarian masses was... Continue Reading

Background and objective: Birth asphyxia is a common pathological condition seen in newborns with increased morbidity and mortality. Grave consequences following birth asphyxia require earlier recognition of the precipitating factors and prompt treatment in intensive care units. Multiple electrolyte imbalance has been related to this condition. This study aimed at determining the mean serum total calcium levels in neonates with birth asphyxia. Methods: This cross sectional study was performed at the neonatal intensive care unit of the Pediatric Department of Fauji Foundation Hospital, Rawalpindi, Pakistan over a period of 6 months. A total of 100 full-term neonates of either gender with evidence of birth asphyxia of any stage were enrolled on their first hour of birth. Serum calcium levels were estimated in each neonate at 24 hours after birth. Results: A total of 60 (60%) neonates were males. Mean serum calcium levels were found to be 7.64 mg/dl ± 0.59... Continue Reading

Background and Objective: The heterogeneous illness known as polycystic ovary syndrome (PCOS) causes multisystem morbidities and is one of the major causes of female infertility. This study aimed at assessing the knowledge and attitude of the young female population towards the early diagnosis of PCOS in Pakistan. Methods: This cross-sectional questionnaire-based survey study was carried out at the Lahore Wapda Hospital Complex, Pakistan over a period of 1 year (January 2021 to 2022). A total of 1,278 females with active PCOS from 18-23 years of age were selected for the study from all provinces of Pakistan. A total of 96 responses were excluded because of inconsistency, incompletion, or duplication while the remaining 1,182 respondents were finally included in the study. Regression analysis, analysis of variance, and t-test were applied for statistical inferences. Results: Only 45.3% of the patients had significant knowledge (p-value = 0.001) or a positive attitude about the... Continue Reading

Background and Objective: Acid–base status is mandatory for clinical assessment of patients with septic shock and severe sepsis. Generally, venous blood gas sample collection is easier, however, the data regarding this approach are lesser defined in our population as a substitute for arterial blood gas (ABG) sample. The present study aimed to determine and compare the pH, pCO2, and bicarbonate levels in VBG and ABG samples in patients with sepsis and septic shock. Method: A cross sectional comparative study was conducted on 350 patients with sepsis and/or septic shock admitted to the medical emergency of Jinnah Hospital, Lahore, Pakistan. Both ABG and VBG samples were collected and pH, pCO2, and bicarbonate levels were determined by standard methods. Data were analyzed using Pearson correlation and the Bland–Altman method for bias. Results: An interclass correlation (r = 0.995, r = 0.929 and r = 0.946) was found for pH, pCO2, and bicarbonate... Continue Reading

Background and Objective: Choosing a career is a difficult decision, especially among young adults, which is influenced by many dynamics. Every adolescent faces the dilemma of choosing a career due to exposure to so many avenues in today’s digitalized world. The objective of this study was to determine the factors influencing the career choices of Generation Z studying in different private colleges in Lahore city of Pakistan. Methods: It was a cross-sectional survey enrolling n = 196 young students of private colleges of Lahore between the age group of 17 and 20 years selected through the convenient sampling technique. An online, validated questionnaire was distributed via WhatsApp groups and the participants were asked to return the filled but anonymous proformas within 1 week. The data compilation and analysis were done by using Statistical Package for Social Sciences software version 26.0 by keeping the level of significance at 5%. Results: The... Continue Reading