Review Article

VOLUME: 36 | ISSUE: 2S | Jun 24, 2020 | PAGE: (169 - 174) | DOI: 10.24911/BioMedica//BioMedica/5-443

Better Diagnostic Modality for COVID-19: CT Chest or RT - PCR? - A Systematic Review


Authors: Seemi Tanvir , Ayesha Fazal , Sadia Sajjad , Shabbir Ahmed


Authors

Seemi Tanvir

Senior Lecturer, General Pathology and Microbiology Department, Margalla Institute of Health Sciences, Rawalpindi- Pakistan.

Ayesha Fazal

Lecturer, General Pathology and Microbiology Department, Margalla Institute of Health Sciences, Rawalpindi- Pakistan.

Sadia Sajjad

Assistant professor/ HoD, Community Dentistry, Department Margalla, Institute of Health Sciences, Rawalpindi- Pakistan..

Shabbir Ahmed

Professor/ HoD, General Pathology and Microbiology Department, Margalla Institute of Health Sciences, Rawalpindi- Pakistan.

Publication History

Received: May 13, 2020

Revised: May 20, 2020

Accepted: June 18, 2020

Published: June 24, 2020


Abstract


Background and Objective: A set of new studies is offering perspective and guidance on the differences between using Real Time Reverse Transcriptase-Polymerase Chain Reaction (RT-PCR) and chest Computerized tomography (CT) in terms of sensitivity and specificity. This review paper addresses the comparative diagnostic potential of CT chest and RT-PCR for COVID-19. Method: An online literature search was carried out from Jan. 2020 to Apr. 2020 from Google -Scholar, Web of Science, Science Direct and PubMed using the MeSH key words. Twenty-five articles were retrieved. Articles with incomplete information and covering other factors like ethnicity were excluded and only the articles with comparison between two clinical diagnostic methods were included. Avoiding the duplication of issues, 5 articles were finally selected for review. Result: This review observed 98% pooled sensitivity of CT-chest being much higher than that of RT-PCR (75%). Conclusion: Patients with suspicion of COVID-19 should be screened using CT scan chest as a more sensitive technique.


Keywords: COVID-19, SARS-CoV-2, CT Chest, RT-PCR


Pubmed Style

Seemi Tanvir, Ayesha Fazal, Sadia Sajjad, Shabbir Ahmed. Better Diagnostic Modality for COVID-19: CT Chest or RT - PCR? - A Systematic Review. BioMedica. 2020; 24 (June 2020): 169-174. doi:10.24911/BioMedica//BioMedica/5-443

Web Style

Seemi Tanvir, Ayesha Fazal, Sadia Sajjad, Shabbir Ahmed. Better Diagnostic Modality for COVID-19: CT Chest or RT - PCR? - A Systematic Review. https://biomedicapk.com/articles/online_first/443 [Access: April 29, 2024]. doi:10.24911/BioMedica//BioMedica/5-443

AMA (American Medical Association) Style

Seemi Tanvir, Ayesha Fazal, Sadia Sajjad, Shabbir Ahmed. Better Diagnostic Modality for COVID-19: CT Chest or RT - PCR? - A Systematic Review. BioMedica. 2020; 24 (June 2020): 169-174. doi:10.24911/BioMedica//BioMedica/5-443

Vancouver/ICMJE Style

Seemi Tanvir, Ayesha Fazal, Sadia Sajjad, Shabbir Ahmed. Better Diagnostic Modality for COVID-19: CT Chest or RT - PCR? - A Systematic Review. BioMedica. (2020), [cited April 29, 2024]; 24 (June 2020): 169-174. doi:10.24911/BioMedica//BioMedica/5-443

Harvard Style

Seemi Tanvir, Ayesha Fazal, Sadia Sajjad, Shabbir Ahmed (2020) Better Diagnostic Modality for COVID-19: CT Chest or RT - PCR? - A Systematic Review. BioMedica, 24 (June 2020): 169-174. doi:10.24911/BioMedica//BioMedica/5-443

Chicago Style

Seemi Tanvir, Ayesha Fazal, Sadia Sajjad, Shabbir Ahmed. "Better Diagnostic Modality for COVID-19: CT Chest or RT - PCR? - A Systematic Review." 24 (2020), 169-174. doi:10.24911/BioMedica//BioMedica/5-443

MLA (The Modern Language Association) Style

Seemi Tanvir, Ayesha Fazal, Sadia Sajjad, Shabbir Ahmed. "Better Diagnostic Modality for COVID-19: CT Chest or RT - PCR? - A Systematic Review." 24.June 2020 (2020), 169-174. Print. doi:10.24911/BioMedica//BioMedica/5-443

APA (American Psychological Association) Style

Seemi Tanvir, Ayesha Fazal, Sadia Sajjad, Shabbir Ahmed (2020) Better Diagnostic Modality for COVID-19: CT Chest or RT - PCR? - A Systematic Review. , 24 (June 2020), 169-174. doi:10.24911/BioMedica//BioMedica/5-443