Review Article

VOLUME: 36 | ISSUE: 3 | Sep 30, 2020 | PAGE: (232 - 247) | DOI: 10.24911/BioMedica/5-101

Application of Ribonucleic Acid (RNA) in Forensic Sciences


Authors: Muhammad Jawad , Saadia Noreen , Muhammad Faheem Ashraf , Maryam Asif , Hafiza Misbah Asif , Saqib Ali , Allah Rakha


Authors

Muhammad Jawad

Department of Forensic Sciences, University of Health Sciences, Lahore – Pakistan.

Saadia Noreen

Department of Forensic Sciences, University of Health Sciences, Lahore – Pakistan

Muhammad Faheem Ashraf

Department of Forensic Sciences, University of Health Sciences, Lahore – Pakistan

Maryam Asif

Multan Medical and Dental College, Multan – Pakistan.

Hafiza Misbah Asif

Multan Medical and Dental College, Multan – Pakistan.

Saqib Ali

Centre of Agricultural Biochemistry and Biotechnology, University of Agriculture, Faisalabad – Pakistan.

Allah Rakha

Head, Department of Forensic Sciences, University of Health Sciences, Lahore – Pakistan

Publication History

Received: April 29, 2020

Revised: July 17, 2020

Accepted: September 22, 2020

Published: September 30, 2020


Abstract


Forensic science has been helping law enforcement agencies in better understanding and presenting the evidence in the court of law. In certain situations, when conventional forensic methods of investigations cannot make better conclusions with more specific accuracy, then molecular techniques do help in reaching the acquired accuracy in the results regarding the identification of evidence. Advanced molecular techniques, which are using Deoxyribose Nucleic acid (DNA), Ribose Nucleic Acid (RNA), and protein molecules to produce forensically important information from the samples recovered at the crime scene. DNA can only distinguish among individuals but is unable to discriminate the type of samples originated from the same sample. For this RNA has become a molecule of interest for its different levels of expressionin different cells/tissues of an individual. RNA molecules of different types are being used to build up models for several purposes (injury-age, new-born age, molecular cause of death, etc.). Modern techniques like Real-time Polymerase Chain Reaction (PCR) and Microarray are being used for the detection of RNA molecules of interest both in the form of its abundance and as a unique molecular detection. This script will help in understanding the importance of RNA application in forensic sciences by providing an overview of the research done to date and the techniques being used for this purpose.


Keywords: Ribose nucleic acid, Genetics, Forensic, Molecular biology, Identification.


Pubmed Style

Muhammad Jawad, Saadia Noreen, Muhammad Faheem Ashraf, Maryam Asif, Hafiza Misbah Asif, Saqib Ali, Allah Rakha. Application of Ribonucleic Acid (RNA) in Forensic Sciences. BioMedica. 2020; 30 (September 2020): 232-247. doi:10.24911/BioMedica/5-101

Web Style

Muhammad Jawad, Saadia Noreen, Muhammad Faheem Ashraf, Maryam Asif, Hafiza Misbah Asif, Saqib Ali, Allah Rakha. Application of Ribonucleic Acid (RNA) in Forensic Sciences. https://biomedicapk.com/articles/online_first/101 [Access: May 06, 2024]. doi:10.24911/BioMedica/5-101

AMA (American Medical Association) Style

Muhammad Jawad, Saadia Noreen, Muhammad Faheem Ashraf, Maryam Asif, Hafiza Misbah Asif, Saqib Ali, Allah Rakha. Application of Ribonucleic Acid (RNA) in Forensic Sciences. BioMedica. 2020; 30 (September 2020): 232-247. doi:10.24911/BioMedica/5-101

Vancouver/ICMJE Style

Muhammad Jawad, Saadia Noreen, Muhammad Faheem Ashraf, Maryam Asif, Hafiza Misbah Asif, Saqib Ali, Allah Rakha. Application of Ribonucleic Acid (RNA) in Forensic Sciences. BioMedica. (2020), [cited May 06, 2024]; 30 (September 2020): 232-247. doi:10.24911/BioMedica/5-101

Harvard Style

Muhammad Jawad, Saadia Noreen, Muhammad Faheem Ashraf, Maryam Asif, Hafiza Misbah Asif, Saqib Ali, Allah Rakha (2020) Application of Ribonucleic Acid (RNA) in Forensic Sciences. BioMedica, 30 (September 2020): 232-247. doi:10.24911/BioMedica/5-101

Chicago Style

Muhammad Jawad, Saadia Noreen, Muhammad Faheem Ashraf, Maryam Asif, Hafiza Misbah Asif, Saqib Ali, Allah Rakha. "Application of Ribonucleic Acid (RNA) in Forensic Sciences." 30 (2020), 232-247. doi:10.24911/BioMedica/5-101

MLA (The Modern Language Association) Style

Muhammad Jawad, Saadia Noreen, Muhammad Faheem Ashraf, Maryam Asif, Hafiza Misbah Asif, Saqib Ali, Allah Rakha. "Application of Ribonucleic Acid (RNA) in Forensic Sciences." 30.September 2020 (2020), 232-247. Print. doi:10.24911/BioMedica/5-101

APA (American Psychological Association) Style

Muhammad Jawad, Saadia Noreen, Muhammad Faheem Ashraf, Maryam Asif, Hafiza Misbah Asif, Saqib Ali, Allah Rakha (2020) Application of Ribonucleic Acid (RNA) in Forensic Sciences. , 30 (September 2020), 232-247. doi:10.24911/BioMedica/5-101