Original Article
VOLUME: 36 | ISSUE: 4 | Dec 31, 2020 | PAGE: (405 - 411) | DOI: 10.24911/BioMedica/5-88
Selective Radical Resection for Unresectable Pancreatic Cancer
Authors: Changku Jia , Ling Liu , Hanzhang Zhu , Weimin Shen , Chunfeng Yang
Article Info
Authors
Changku Jia
Department of Hepatopancreatobiliary Surgery, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Zhejiang Clinical Research Center of Hepatobiliary and Pancreatic Diseases, No. 261, Huansha Road, Hangzhou 310006, China.
Ling Liu
Department of Hepatopancreatobiliary Surgery, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Zhejiang Clinical Research Center of Hepatobiliary and Pancreatic Diseases, No. 261, Huansha Road, Hangzhou 310006, China.
Hanzhang Zhu
Department of Hepatopancreatobiliary Surgery, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Zhejiang Clinical Research Center of Hepatobiliary and Pancreatic Diseases, No. 261, Huansha Road, Hangzhou 310006, China.
Weimin Shen
Department of Hepatopancreatobiliary Surgery, Affiliated Hangzhou First People's Hospital, Zhejiang University School of Medicine, Zhejiang Clinical Research Center of Hepatobiliary and Pancreatic Diseases, No. 261, Huansha Road, Hangzhou 310006, China.
Chunfeng Yang
Department of Hepatopancreatobiliary Surgery, Xiaoshan Hospital, Zhejiang, No. 728, Yucaibei Road, Hangzhou 311202, China.
Publication History
Received: October 29, 2020
Revised: December 01, 2020
Accepted: December 14, 2020
Published: December 31, 2020
Abstract
Background and Objective: For inefficiency of chemotherapy and radiation against pancreatic cancer, resection rate for primary unresectable pancreatic cancer remains very low. This study was carried out to evaluate the safety and value of radical resection for unresectable pancreatic cancer (UPC).
Methods: Clinical data were analyzed retrospectively. In unresectable group, 360° resection of the involved artery sheath, resection and reconstruction of the involved artery, resection and reconstruction of the involved vein as well as resection and reconstruction of combined organs were performed. Operation time, intraoperative blood loss, ICU transitional treatment, pancreatic fistula, bleeding, reoperation and survival time were analyzed for two groups.
Results: Operation time and intraoperative blood loss were greatly increased in the unresectable group. The incidence of intractable diarrhea and abdominal hemorrhage in the unresectable group were higher. However, the rate of ICU transitional therapy, delayed gastric emptying and reoperation were lower. Grade-C pancreatic fistula occurred in neither group.
Conclusion: Surgical treatment through stringent selection for patients with unresectable pancreatic cancer is a safer technique and median post-operative survival time is similar to patients with resectable pancreatic cancer.
Keywords: Pancreatic cancer, Radical resection, Complications, Survival time, Prognosis
Pubmed Style
Changku Jia, Ling Liu, Hanzhang Zhu, Weimin Shen, Chunfeng Yang. Selective Radical Resection for Unresectable Pancreatic Cancer. BioMedica. 2020; 31 (December 2020): 405-411. doi:10.24911/BioMedica/5-88
Web Style
Changku Jia, Ling Liu, Hanzhang Zhu, Weimin Shen, Chunfeng Yang. Selective Radical Resection for Unresectable Pancreatic Cancer. https://biomedicapk.com/articles/online_first/88 [Access: April 29, 2024]. doi:10.24911/BioMedica/5-88
AMA (American Medical Association) Style
Changku Jia, Ling Liu, Hanzhang Zhu, Weimin Shen, Chunfeng Yang. Selective Radical Resection for Unresectable Pancreatic Cancer. BioMedica. 2020; 31 (December 2020): 405-411. doi:10.24911/BioMedica/5-88
Vancouver/ICMJE Style
Changku Jia, Ling Liu, Hanzhang Zhu, Weimin Shen, Chunfeng Yang. Selective Radical Resection for Unresectable Pancreatic Cancer. BioMedica. (2020), [cited April 29, 2024]; 31 (December 2020): 405-411. doi:10.24911/BioMedica/5-88
Harvard Style
Changku Jia, Ling Liu, Hanzhang Zhu, Weimin Shen, Chunfeng Yang (2020) Selective Radical Resection for Unresectable Pancreatic Cancer. BioMedica, 31 (December 2020): 405-411. doi:10.24911/BioMedica/5-88
Chicago Style
Changku Jia, Ling Liu, Hanzhang Zhu, Weimin Shen, Chunfeng Yang. "Selective Radical Resection for Unresectable Pancreatic Cancer." 31 (2020), 405-411. doi:10.24911/BioMedica/5-88
MLA (The Modern Language Association) Style
Changku Jia, Ling Liu, Hanzhang Zhu, Weimin Shen, Chunfeng Yang. "Selective Radical Resection for Unresectable Pancreatic Cancer." 31.December 2020 (2020), 405-411. Print. doi:10.24911/BioMedica/5-88
APA (American Psychological Association) Style
Changku Jia, Ling Liu, Hanzhang Zhu, Weimin Shen, Chunfeng Yang (2020) Selective Radical Resection for Unresectable Pancreatic Cancer. , 31 (December 2020), 405-411. doi:10.24911/BioMedica/5-88