BioMedica |

Original Article

VOLUME: 35 | ISSUE: 4 | Dec 30, 2019 | PAGE: (214 - 217) | DOI: 10.51441.BioMedica.5-471

Effect of Aqueous Garlic Extract on Monosodium Glutamate Induced Weight Loss in Wistar Rats

Authors: Hafiza Sadia Ahmed , Fatima Inam , Rabia Sajjad Toor , Roomana Hashim , Asia Nazeer , Fauzia Qureshi

Article Info

Authors

Hafiza Sadia Ahmed

Department of Anatomy, Amna Inayat Medical College, Sheikhupura-Pakistan.

Fatima Inam

Akhtar Saeed Medical College, Lahore-Pakistan.

Rabia Sajjad Toor

Sahara Medical College-Narowal.

Roomana Hashim

Akhtar Saeed Medical College, Lahore-Pakistan.

Asia Nazeer

Department of Anatomy, Amna Inayat Medical College, Sheikhupura-Pakistan.

Fauzia Qureshi

Azra Naheed Medical College, Lahore-Pakistan.

Publication History

Received: August 03, 2019

Revised: September 30, 2019

Accepted: December 12, 2019

Published: December 30, 2019

Abstract

Background and Objective: Monosodium glutamate (MSG) is used as a taste enhancer and is a common ingredient of some foods as canned vegetables, soups, processed meat and traditional seasoning. Garlic, on the other hand, is known to have antibacterial and antiviral effects and has also been used for cancer prevention. The objective of current study is to observe the effect of aqueous garlic extract (AGE) in MSG induced toxic effects on the body weight of adult Wistar rats.
Methods: The present study was carried out in the Department of Anatomy at University of Health Sciences, Lahore in 2016. A total of 24 adult male Wistar rats, 6-8 weeks old of 150-175 grams weight were taken and divided into four groups (6 rats in each). Group A served as a control and received 6 ml/kg of distilled water orally via gavage tube and intraperitoneally for 14 days; Group B was treated with MSG 4 gm/kg dissolved in 6 ml of distilled water administered intraperitoneally for 14 days;
Group C was treated with AGE 200 mg/kg dissolved in 0.4 ml of distilled water orally by gavage tube for 14 days and Group D was given 4 gm/kg MSG dissolved in 6ml of distilled water, intraperitoneally first, followed by AGE 200 mg/kg dissolved in 0.4 ml of distilled water, orally, by gavage tube for a period of 14 days. All doses were given once a day.
Results: At the end of study, the body weight of rats in MSG treated group was found to be decreased and was statistically significant (P < 0.003) and garlic did counter the effects of MSG though not significantly.
Conclusion: Aqueous garlic extract improves the deleterious effects of MSG on the body weight of Wistar rats.

Keywords: Monosodium glutamate (MSG), Body weight, Aqueous garlic extract (AGE).

Pubmed Style

Hafiza Sadia Ahmed, Fatima Inam, Rabia Sajjad Toor, Roomana Hashim, Asia Nazeer, Fauzia Qureshi. Effect of Aqueous Garlic Extract on Monosodium Glutamate Induced Weight Loss in Wistar Rats. BioMedica. 2019; 30 (December 2019): 214-217. doi:10.51441.BioMedica.5-471

Web Style

Hafiza Sadia Ahmed, Fatima Inam, Rabia Sajjad Toor, Roomana Hashim, Asia Nazeer, Fauzia Qureshi. Effect of Aqueous Garlic Extract on Monosodium Glutamate Induced Weight Loss in Wistar Rats. https://biomedicapk.com/articles/online_first/471 [Access: May 07, 2024]. doi:10.51441.BioMedica.5-471

AMA (American Medical Association) Style

Vancouver/ICMJE Style

Hafiza Sadia Ahmed, Fatima Inam, Rabia Sajjad Toor, Roomana Hashim, Asia Nazeer, Fauzia Qureshi. Effect of Aqueous Garlic Extract on Monosodium Glutamate Induced Weight Loss in Wistar Rats. BioMedica. (2019), [cited May 07, 2024]; 30 (December 2019): 214-217. doi:10.51441.BioMedica.5-471

Harvard Style

Hafiza Sadia Ahmed, Fatima Inam, Rabia Sajjad Toor, Roomana Hashim, Asia Nazeer, Fauzia Qureshi (2019) Effect of Aqueous Garlic Extract on Monosodium Glutamate Induced Weight Loss in Wistar Rats. BioMedica, 30 (December 2019): 214-217. doi:10.51441.BioMedica.5-471

Chicago Style

Hafiza Sadia Ahmed, Fatima Inam, Rabia Sajjad Toor, Roomana Hashim, Asia Nazeer, Fauzia Qureshi. "Effect of Aqueous Garlic Extract on Monosodium Glutamate Induced Weight Loss in Wistar Rats." 30 (2019), 214-217. doi:10.51441.BioMedica.5-471

MLA (The Modern Language Association) Style

APA (American Psychological Association) Style

Hafiza Sadia Ahmed, Fatima Inam, Rabia Sajjad Toor, Roomana Hashim, Asia Nazeer, Fauzia Qureshi (2019) Effect of Aqueous Garlic Extract on Monosodium Glutamate Induced Weight Loss in Wistar Rats. , 30 (December 2019), 214-217. doi:10.51441.BioMedica.5-471