BioMedica |

Original Article

VOLUME: 35 | ISSUE: 2 | Jun 24, 2019 | PAGE: (72 - 75) | DOI: 10.51441.BioMedica.5-517

Fetomaternal Outcome of Pregnancy with Hepatitis E Infection

Authors: Aalia Tayyba , Hafiz Mohammed Dawood , Nusrat Manzoor , Sundus Waheed , Gul-e-Raana , Asma Saadia

Article Info

Authors

Aalia Tayyba

Department of Obstetrics and Gynaecology, Amna Inayat Medical College, Sheikhupura-Pakistan.

Hafiz Mohammed Dawood

Department of Community Medicine, Sahara Medical College, Narowal- Pakistan.

Nusrat Manzoor

Rai Medical College, Sargodha-Pakistan.

Sundus Waheed

Department of Public Health, University of Health Sciences, Lahore-Pakistan.

Gul-e-Raana

Department of Obstetrics and Gynaecology, Services Hospital, Lahore- Pakistan.

Asma Saadia

Department of Pathology, Shalamar Medical & Dental College, Lahore – Pakistan.

Publication History

Received: January 20, 2019

Revised: March 31, 2019

Accepted: June 19, 2019

Published: June 24, 2019

Abstract

Background and Objective: Hepatitis E viral infection is one of the major health concerns in the pregnant women owing to its fulminant nature in pregnancy and contribution to increase the mortality in pregnant women as compared to non-pregnant females. So, this study was conducted with an objective to find out the pregnancy related mortality, maternal morbidity and fetal outcome suffering with hepatitis E (HEV) in pregnancy.
Methods: This study was conducted in Hussain Memorial Hospital Lahore and Sir Ganga Ram Hospital, Lahore for the period of one year and seven months between May 2017 and November 2018. This cross sectional study recruited 60 females with serologically proven HEV in pregnancy. All of these targeted patients were admitted in the aforesaid hospital and followed with coagulation profile and liver function test. The record of maternal mortality, morbidity and fetal outcome was duly maintained.
Results: More maternal morbidity was noted in patients who were admitted in the third trimester with clinical disease and based on laboratory results i.e. the derangement of haematological and biochemical tests. Of the 60 targeted patients, majority of the patients (73.33%) were discharged home safely, therefore, remaining patients were expired with the overall mortality rate of 26.67%. Moreover, perinatal mortality rate was recorded as 30.3 per 1000 live birth.
Conclusion: In conclusion, Hepatitis E is a serious issue in underdeveloped and developing countries with high maternal morbidity and mortality rates in pregnancy especially last trimester. It also increases the risk of perinatal mortality, morbidity and preterm delivery.

Keywords: Perinatal mortality, Liver failure, Acute, Hepatitis E virus, Maternal mortality.

Pubmed Style

Aalia Tayyba, Hafiz Mohammed Dawood, Nusrat Manzoor, Sundus Waheed, Gul-e-Raana, Asma Saadia. Fetomaternal Outcome of Pregnancy with Hepatitis E Infection. BioMedica. 2019; 24 (June 2019): 72-75. doi:10.51441.BioMedica.5-517

Web Style

Aalia Tayyba, Hafiz Mohammed Dawood, Nusrat Manzoor, Sundus Waheed, Gul-e-Raana, Asma Saadia. Fetomaternal Outcome of Pregnancy with Hepatitis E Infection. https://biomedicapk.com/articles/online_first/517 [Access: May 03, 2024]. doi:10.51441.BioMedica.5-517

AMA (American Medical Association) Style

Vancouver/ICMJE Style

Aalia Tayyba, Hafiz Mohammed Dawood, Nusrat Manzoor, Sundus Waheed, Gul-e-Raana, Asma Saadia. Fetomaternal Outcome of Pregnancy with Hepatitis E Infection. BioMedica. (2019), [cited May 03, 2024]; 24 (June 2019): 72-75. doi:10.51441.BioMedica.5-517

Harvard Style

Aalia Tayyba, Hafiz Mohammed Dawood, Nusrat Manzoor, Sundus Waheed, Gul-e-Raana, Asma Saadia (2019) Fetomaternal Outcome of Pregnancy with Hepatitis E Infection. BioMedica, 24 (June 2019): 72-75. doi:10.51441.BioMedica.5-517

Chicago Style

Aalia Tayyba, Hafiz Mohammed Dawood, Nusrat Manzoor, Sundus Waheed, Gul-e-Raana, Asma Saadia. "Fetomaternal Outcome of Pregnancy with Hepatitis E Infection." 24 (2019), 72-75. doi:10.51441.BioMedica.5-517

MLA (The Modern Language Association) Style

Aalia Tayyba, Hafiz Mohammed Dawood, Nusrat Manzoor, Sundus Waheed, Gul-e-Raana, Asma Saadia. "Fetomaternal Outcome of Pregnancy with Hepatitis E Infection." 24.June 2019 (2019), 72-75. Print. doi:10.51441.BioMedica.5-517

APA (American Psychological Association) Style

Aalia Tayyba, Hafiz Mohammed Dawood, Nusrat Manzoor, Sundus Waheed, Gul-e-Raana, Asma Saadia (2019) Fetomaternal Outcome of Pregnancy with Hepatitis E Infection. , 24 (June 2019), 72-75. doi:10.51441.BioMedica.5-517