Original Article
VOLUME: 35 | ISSUE: 1 | Mar 21, 2019 | PAGE: (41 - 44) | DOI: 10.51441.BioMedica.5-535
Relationship of CD4++ Count with Viral Load in HIV/AIDS Patients
Authors: Javaid M.I , Nawaz R , Natiq M , Haider S , Mazhar S , Ghazanfar M. , Ahmad R , Anwar A
Article Info
Authors
Javaid M.I
Assistant Professor Pathology, Allama Iqbal Medical College, Lahore – Pakistan.
Nawaz R
Department of Pathology, Allama Iqbal Medical College, Lahore – Pakistan.
Natiq M
Department of Pathology, Allama Iqbal Medical College, Lahore – Pakistan.
Haider S
Department of Pathology, Allama Iqbal Medical College, Lahore – Pakistan.
Mazhar S
Department of Pathology, Allama Iqbal Medical College, Lahore – Pakistan.
Ghazanfar M.
Department of Pathology, Allama Iqbal Medical College, Lahore – Pakistan.
Ahmad R
Department of Pathology, Allama Iqbal Medical College, Lahore – Pakistan.
Anwar A
Department of Pathology, Allama Iqbal Medical College, Lahore – Pakistan.
Publication History
Received: October 02, 2018
Revised: December 19, 2018
Accepted: March 11, 2019
Published: March 21, 2019
Abstract
Background and Objective: CD4+ cell counts and viral loads are the parameters which are used to monitor the health status in individuals infected with Human Immunodeficiency Virus (HIV). Viral load affects CD4+ counts, as high levels of virus in blood causes reduction in CD4+ counts leading to symptomatic disease in future. This study was aimed to determine the relationship between CD4+ cell count and viral load in HIV patients.
Methods: One hundred six (106) HIV positive patients presenting at the Pathology laboratory of Allama Iqbal Medical College, Lahore, Pakistan were enrolled for the study. CD4+ counts and viral loads were measured. Association between two parameters was calculated by applying statistical tests. A P value of less than or equal to 0.05 was considered as statistically significant.
Results: Of the total 106 patients, there were 83 (78.3%) male 17 (16%) female patients and 6 (5.7%) transgenders. Majority of the study population 50/106 (47.2%) had CD4+ lymphocyte count ≥ 500/µl, 38/ 106 (35.8%) cases had CD4+ lymphocyte count in the range of 200 – 499/µl, while CD4+ lymphocyte count < 200/µl was seen in 18/106 (17%) cases. Reciprocal relationship was observed between CD4+ count and viral loads. Statistically significant difference was observed (P = 0.012).
Conclusion: CD4+ cell count and viral load are utilized as predictors of progression and severity of HIV infection.
Keywords: Human Immunodeficiency Virus, CD4+ cell count, Viral load
Pubmed Style
Javaid M.I, Nawaz R, Natiq M, Haider S, Mazhar S, Ghazanfar M., Ahmad R, Anwar A. Relationship of CD4++ Count with Viral Load in HIV/AIDS Patients. BioMedica. 2019; 21 (March 2019): 41-44. doi:10.51441.BioMedica.5-535
Web Style
Javaid M.I, Nawaz R, Natiq M, Haider S, Mazhar S, Ghazanfar M., Ahmad R, Anwar A. Relationship of CD4++ Count with Viral Load in HIV/AIDS Patients. https://biomedicapk.com/articles/online_first/535 [Access: May 04, 2024]. doi:10.51441.BioMedica.5-535
AMA (American Medical Association) Style
Javaid M.I, Nawaz R, Natiq M, Haider S, Mazhar S, Ghazanfar M., Ahmad R, Anwar A. Relationship of CD4++ Count with Viral Load in HIV/AIDS Patients. BioMedica. 2019; 21 (March 2019): 41-44. doi:10.51441.BioMedica.5-535
Vancouver/ICMJE Style
Javaid M.I, Nawaz R, Natiq M, Haider S, Mazhar S, Ghazanfar M., Ahmad R, Anwar A. Relationship of CD4++ Count with Viral Load in HIV/AIDS Patients. BioMedica. (2019), [cited May 04, 2024]; 21 (March 2019): 41-44. doi:10.51441.BioMedica.5-535
Harvard Style
Javaid M.I, Nawaz R, Natiq M, Haider S, Mazhar S, Ghazanfar M., Ahmad R, Anwar A (2019) Relationship of CD4++ Count with Viral Load in HIV/AIDS Patients. BioMedica, 21 (March 2019): 41-44. doi:10.51441.BioMedica.5-535
Chicago Style
Javaid M.I, Nawaz R, Natiq M, Haider S, Mazhar S, Ghazanfar M., Ahmad R, Anwar A. "Relationship of CD4++ Count with Viral Load in HIV/AIDS Patients." 21 (2019), 41-44. doi:10.51441.BioMedica.5-535
MLA (The Modern Language Association) Style
Javaid M.I, Nawaz R, Natiq M, Haider S, Mazhar S, Ghazanfar M., Ahmad R, Anwar A. "Relationship of CD4++ Count with Viral Load in HIV/AIDS Patients." 21.March 2019 (2019), 41-44. Print. doi:10.51441.BioMedica.5-535
APA (American Psychological Association) Style
Javaid M.I, Nawaz R, Natiq M, Haider S, Mazhar S, Ghazanfar M., Ahmad R, Anwar A (2019) Relationship of CD4++ Count with Viral Load in HIV/AIDS Patients. , 21 (March 2019), 41-44. doi:10.51441.BioMedica.5-535