Original Article

Volume 37, Issue 3 Page (1 - 17)

https://doi.org/10.51441.BioMedica.5-497

Clinical and Laboratory Characteristics of COVID-19 Infection in Patients Presenting to A Tertiary Care Hospital


Authors: Huma Batool, Asifa Karamat, Khalid Waheed, Sohail Anwar, Syed Arslan Haider, Syed Mazhar Ali Naqvi, Munaza Javed


Authors

Huma Batool

Department of Pulmonology, Lahore General Hospital, Lahore-Pakistan.

Asifa Karamat

Assistant Professor of Pulmonology, Department of Tuberculosis and Chest Medicine, Gulab Devi Hospital, Lahore - Pakistan.

Khalid Waheed

Professor of Pulmonology & Sleep Medicine, Lahore General Hospital, Lahore- Pakistan.

Sohail Anwar

Assistant Professor of Pulmonology, University of Lahore Teaching Hospital, Lahore-Pakistan.

Syed Arslan Haider

Assistant Professor of Neurology, PINS, Lahore General Hospital, Lahore- Pakistan.

Syed Mazhar Ali Naqvi

Associate Professor of Pulmonary and Critical Medicine / MICU, Services Hospital, Lahore- Pakistan.

Munaza Javed

Associate Professor of Medicine, Azra Naheed Medical College, Lahore- Pakistan.

Publication History

Received: September 28, 2021

Accepted:

Published: September 30, 2021


Abstract


Background and Objective: COVID-19 disease is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) having a wide variety of clinical features ranging from asymptomatic carriers to respiratory failure requiring mechanical ventilation. The objective of the study was to analyze the spectrum of different symptoms, laboratory findings and complications in patients who were admitted in either COVID ward or intensive care unit (ICU) of a local hospital.

Methods: A retrospective cohort study of the medical records of 100 COVID-19 disease patients with PCR detected SARS-CoV-2 infection were collected. Participant information was retrospectively obtained from the hospital medical records which included clinical records and laboratory findings. All statistical analyses were done using Statistical Package for the Social Sciences (SPSS) version 21.

Results: The mean age of the patients was 50.8 ±5.86 with male predominance (79%). Most frequent co-morbidities were diabetes mellitus (42%) and hypertension (36%). Most frequent symptoms were fever (95.9%) and fatigue (95.9%) followed by dry cough (86.5%), myalgia (85.1) and shortness of breath (70%). Amongst the patients admitted, leukocyte count was 10.95 x 103, C-reactive protein (CRP) was 12.8mg/dl, ferritin was 730.8ng/ml and Lactate Dehydrogenase (LDH) was found to be 1254.7 U/l. Hepatic and renal functions were borderline deranged.

Conclusion: COVID-19 disease has a wide spectrum of clinical symptoms. Patients with raised inflammatory markers have severe disease and are more likely in need of an ICU care. By carefully observing these markers may help in better management of COVID-19 disease.


Keywords: Coronavirus, Intensive care unit, COVID-19, Complications, Laboratory markers.



Pubmed Style

Huma Batool, Asifa Karamat, Khalid Waheed, Sohail Anwar, Syed Arslan Haider, Syed Mazhar Ali Naqvi, Munaza Javed. Clinical and Laboratory Characteristics of COVID-19 Infection in Patients Presenting to A Tertiary Care Hospital. biomedica. 2021; 30 (September 2021): 86-91. doi:10.51441.BioMedica.5-497

Web Style

Huma Batool, Asifa Karamat, Khalid Waheed, Sohail Anwar, Syed Arslan Haider, Syed Mazhar Ali Naqvi, Munaza Javed. Clinical and Laboratory Characteristics of COVID-19 Infection in Patients Presenting to A Tertiary Care Hospital. https://biomedicapk.com/10.51441/BioMedica/5-497 [Access: October 21, 2021]. doi:10.51441.BioMedica.5-497

AMA (American Medical Association) Style

Huma Batool, Asifa Karamat, Khalid Waheed, Sohail Anwar, Syed Arslan Haider, Syed Mazhar Ali Naqvi, Munaza Javed. Clinical and Laboratory Characteristics of COVID-19 Infection in Patients Presenting to A Tertiary Care Hospital. biomedica. 2021; 30 (September 2021): 86-91. doi:10.51441.BioMedica.5-497

Vancouver/ICMJE Style

Huma Batool, Asifa Karamat, Khalid Waheed, Sohail Anwar, Syed Arslan Haider, Syed Mazhar Ali Naqvi, Munaza Javed. Clinical and Laboratory Characteristics of COVID-19 Infection in Patients Presenting to A Tertiary Care Hospital. biomedica. (2021), [cited October 21, 2021]; 30 (September 2021): 86-91. doi:10.51441.BioMedica.5-497

Harvard Style

Huma Batool, Asifa Karamat, Khalid Waheed, Sohail Anwar, Syed Arslan Haider, Syed Mazhar Ali Naqvi, Munaza Javed (2021) Clinical and Laboratory Characteristics of COVID-19 Infection in Patients Presenting to A Tertiary Care Hospital. biomedica, 30 (September 2021): 86-91. doi:10.51441.BioMedica.5-497

Turabian Style

Huma Batool, Asifa Karamat, Khalid Waheed, Sohail Anwar, Syed Arslan Haider, Syed Mazhar Ali Naqvi, Munaza Javed. 2021. Clinical and Laboratory Characteristics of COVID-19 Infection in Patients Presenting to A Tertiary Care Hospital. Biomedica, 30 (September 2021): 86-91. doi:10.51441.BioMedica.5-497

Chicago Style

Huma Batool, Asifa Karamat, Khalid Waheed, Sohail Anwar, Syed Arslan Haider, Syed Mazhar Ali Naqvi, Munaza Javed. "Clinical and Laboratory Characteristics of COVID-19 Infection in Patients Presenting to A Tertiary Care Hospital." Biomedica 30 (2021), 86-91. doi:10.51441.BioMedica.5-497

MLA (The Modern Language Association) Style

Huma Batool, Asifa Karamat, Khalid Waheed, Sohail Anwar, Syed Arslan Haider, Syed Mazhar Ali Naqvi, Munaza Javed. "Clinical and Laboratory Characteristics of COVID-19 Infection in Patients Presenting to A Tertiary Care Hospital." Biomedica 30.September 2021 (2021), 86-91. Print. doi:10.51441.BioMedica.5-497

APA (American Psychological Association) Style

Huma Batool, Asifa Karamat, Khalid Waheed, Sohail Anwar, Syed Arslan Haider, Syed Mazhar Ali Naqvi, Munaza Javed (2021) Clinical and Laboratory Characteristics of COVID-19 Infection in Patients Presenting to A Tertiary Care Hospital. Biomedica, 30 (September 2021), 86-91. doi:10.51441.BioMedica.5-497