Original Article

Volume 37, Issue 3 Page (1 - )

https://doi.org/10.51441.BioMedica.5-501

Trucut Biopsy As A First Line Diagnostic Modality for Equivocal or Suspicious Breast Masses: An Experience from a Teaching Hospital in Khyber Pakhtunkhwa


Authors: Sheikh Qais Falah, Iram Bashir, Arshad Ali Marwat, Asif Shams


Authors

Sheikh Qais Falah

Associate Professor, Department of Surgery, Gomal Medical College, Dera Ismail Khan- Pakistan.

Iram Bashir

Senior Registrar, Surgical Unit, Mufti Mehmood Memorial Teaching Hospital, Dera Ismail Khan- Pakistan.

Arshad Ali Marwat

Professor of Surgery, Gomal Medical College, Dera Ismail Khan- Pakistan.

Asif Shams

Medical Officer, Surgical Unit, Mufti Mehmood Memorial Teaching Hospital, Dera Ismail Khan- Pakistan.

Publication History

Received: September 28, 2021

Accepted:

Published: September 30, 2021


Abstract


Background and Objective: Trucut biopsy (TCB) is a commonly used technique for histopathological diagnosis of a clinically and radiologically equivocal or suspicious breast mass. This study aimed to determine the sensitivity and specificity of trucut biopsy in the diagnosis of equivocal or suspicious breast masses at local tertiary care hospital in Khyber Pukhtunkhwa. 

Methods: This descriptive cross sectional study was conducted at the surgical unit of Mufti Mehmood Memorial Teaching Hospital (MMMTH), Dera Ismail Khan, Pakistan. The study included 80 patients who presented with equivocal or suspicious breast masses from September, 2015 till December, 2020. The patients underwent TCB and after the histopathology report, they were followed by a diagnosis made on the definitive surgical procedure. The histopathology diagnosis following TCB was compared with the histopathology report of postsurgical specimen to determine the sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) of TCB taking post-surgery histopathology as a gold standard for diagnosis.   

Results: Out of the 80 patients, 68 (85%) were found to have a primary breast malignancy while 12 (15%) patients were diagnosed with non-malignant lesions. There were only two false negative cases. The specificity and PPV of TCB were found to be 100%, while a sensitivity of 97% and a NPV of 85.7% was calculated.

Conclusion: Trucut biopsy is a valid, reliable and simple first line minimally invasive method to determine the diagnosis of breast masses that are clinically and radiologically (BIRADS 3 to 5) equivocal or suspicious. 


Keywords: Trucut biopsy; Breast mass; Equivocal; Phyllodes tumor; Breast carcinoma.



Pubmed Style

Sheikh Qais Falah, Iram Bashir, Arshad Ali Marwat, Asif Shams. Trucut Biopsy As A First Line Diagnostic Modality for Equivocal or Suspicious Breast Masses: An Experience from a Teaching Hospital in Khyber Pakhtunkhwa. biomedica. 2021; 30 (September 2021): 86-91. doi:10.51441.BioMedica.5-501

Web Style

Sheikh Qais Falah, Iram Bashir, Arshad Ali Marwat, Asif Shams. Trucut Biopsy As A First Line Diagnostic Modality for Equivocal or Suspicious Breast Masses: An Experience from a Teaching Hospital in Khyber Pakhtunkhwa. https://biomedicapk.com/10.51441/BioMedica/5-501 [Access: October 21, 2021]. doi:10.51441.BioMedica.5-501

AMA (American Medical Association) Style

Sheikh Qais Falah, Iram Bashir, Arshad Ali Marwat, Asif Shams. Trucut Biopsy As A First Line Diagnostic Modality for Equivocal or Suspicious Breast Masses: An Experience from a Teaching Hospital in Khyber Pakhtunkhwa. biomedica. 2021; 30 (September 2021): 86-91. doi:10.51441.BioMedica.5-501

Vancouver/ICMJE Style

Sheikh Qais Falah, Iram Bashir, Arshad Ali Marwat, Asif Shams. Trucut Biopsy As A First Line Diagnostic Modality for Equivocal or Suspicious Breast Masses: An Experience from a Teaching Hospital in Khyber Pakhtunkhwa. biomedica. (2021), [cited October 21, 2021]; 30 (September 2021): 86-91. doi:10.51441.BioMedica.5-501

Harvard Style

Sheikh Qais Falah, Iram Bashir, Arshad Ali Marwat, Asif Shams (2021) Trucut Biopsy As A First Line Diagnostic Modality for Equivocal or Suspicious Breast Masses: An Experience from a Teaching Hospital in Khyber Pakhtunkhwa. biomedica, 30 (September 2021): 86-91. doi:10.51441.BioMedica.5-501

Turabian Style

Sheikh Qais Falah, Iram Bashir, Arshad Ali Marwat, Asif Shams. 2021. Trucut Biopsy As A First Line Diagnostic Modality for Equivocal or Suspicious Breast Masses: An Experience from a Teaching Hospital in Khyber Pakhtunkhwa. Biomedica, 30 (September 2021): 86-91. doi:10.51441.BioMedica.5-501

Chicago Style

Sheikh Qais Falah, Iram Bashir, Arshad Ali Marwat, Asif Shams. "Trucut Biopsy As A First Line Diagnostic Modality for Equivocal or Suspicious Breast Masses: An Experience from a Teaching Hospital in Khyber Pakhtunkhwa." Biomedica 30 (2021), 86-91. doi:10.51441.BioMedica.5-501

MLA (The Modern Language Association) Style

Sheikh Qais Falah, Iram Bashir, Arshad Ali Marwat, Asif Shams. "Trucut Biopsy As A First Line Diagnostic Modality for Equivocal or Suspicious Breast Masses: An Experience from a Teaching Hospital in Khyber Pakhtunkhwa." Biomedica 30.September 2021 (2021), 86-91. Print. doi:10.51441.BioMedica.5-501

APA (American Psychological Association) Style

Sheikh Qais Falah, Iram Bashir, Arshad Ali Marwat, Asif Shams (2021) Trucut Biopsy As A First Line Diagnostic Modality for Equivocal or Suspicious Breast Masses: An Experience from a Teaching Hospital in Khyber Pakhtunkhwa. Biomedica, 30 (September 2021), 86-91. doi:10.51441.BioMedica.5-501