Original Article

Volume 37, Issue 3 Page (1 - 23)

https://doi.org/10.51441.BioMedica.5-503

Prednisone Combined with Antiviral Agents for the Treatment of Early Idiopathic Brachial Plexus Neuritis: Report of 5 Cases


Authors: Xueyuan Li, Miaozhong Li, Miao Yu, Kyaw Thura, Xiaoling Zhou, Chen Hong


Authors

Xueyuan Li

Department of Hand Surgery, Ningbo Sixth Hospital, Zhejiang- China.

Miaozhong Li

Department of Hand Surgery, Ningbo Sixth Hospital, Zhejiang- China.

Miao Yu

Department of Hand Surgery, Ningbo Sixth Hospital, Zhejiang- China.

Kyaw Thura

Mandalay Orthopaedic Hospital, University of Medicine, Mandalay - Myanmar.

Xiaoling Zhou

Department of Hand Surgery, Ningbo Sixth Hospital, Zhejiang- China.

Chen Hong

Department of Hand Surgery, Ningbo Sixth Hospital, Zhejiang –China.

Publication History

Received: September 28, 2021

Accepted:

Published: September 30, 2021


Abstract


Background and objectives: The aim of this study was to report the short-term outcomes of early idiopathic brachial plexus neuritis after low dose corticosteroid combined with antiviral agent.

Methods: Five patients with early brachial plexus neuritis presenting from April to June 2019 were included in this study. According to individual patient conditions, electromyography (EMG), nerve B-ultrasound and/or brachial plexus magnetic resonance imaging (MRI) was performed. After the diagnosis was confirmed, modified conservative treatments were initiated, including low dose corticosteroid therapy and antiviral therapy for 2 weeks each while neurotrophic therapy for 4 weeks.

Results: Of the 5 patients, only 2 patients had symptoms of pain at onset, and 3 patients had sensory disturbances. Two patients reported a common cold before onset. The lesion involved the upper trunk of the brachial plexus in 2 patients. MRI showed slightly intense signals, of which 1 patient also had supraclavicular lymph node augmentation. The other 3 patients suffered ipsilateral radial nerve palsy. At 1 month of modified treatment, 4 patients recovered well with almost complete shoulder and hand movements; however, their muscle strength was still weaker comparing with the contralateral side. 1 patient restored full range of motion after surgery in 2 months.

Conclusion: Early treatment is the key to good prognosis in patients with brachial plexus neuritis. Antiviral therapy combined with low-dose corticosteroid therapy may be superior to traditional treatment alone. In terms of early diagnosis, the clinical value of imaging examinations such as ultrasound and MRI is more specific as compared to that of EMG.


Keywords: Brachial plexus neuritis, Treatment, Corticosteroid, Neuralgic amyotrophy, Antiviral.



Pubmed Style

Xueyuan Li, Miao Yu, Miaozhong Li, Kyaw Thura, Xiaoling Zhou, Chen Hong. Prednisone Combined with Antiviral Agents for the Treatment of Early Idiopathic Brachial Plexus Neuritis: Report of 5 Cases. biomedica. 2021; 30 (September 2021): 86-91. doi:10.51441.BioMedica.5-503

Web Style

Xueyuan Li, Miao Yu, Miaozhong Li, Kyaw Thura, Xiaoling Zhou, Chen Hong. Prednisone Combined with Antiviral Agents for the Treatment of Early Idiopathic Brachial Plexus Neuritis: Report of 5 Cases. https://biomedicapk.com/10.51441/BioMedica/5-503 [Access: October 21, 2021]. doi:10.51441.BioMedica.5-503

AMA (American Medical Association) Style

Xueyuan Li, Miao Yu, Miaozhong Li, Kyaw Thura, Xiaoling Zhou, Chen Hong. Prednisone Combined with Antiviral Agents for the Treatment of Early Idiopathic Brachial Plexus Neuritis: Report of 5 Cases. biomedica. 2021; 30 (September 2021): 86-91. doi:10.51441.BioMedica.5-503

Vancouver/ICMJE Style

Xueyuan Li, Miao Yu, Miaozhong Li, Kyaw Thura, Xiaoling Zhou, Chen Hong. Prednisone Combined with Antiviral Agents for the Treatment of Early Idiopathic Brachial Plexus Neuritis: Report of 5 Cases. biomedica. (2021), [cited October 21, 2021]; 30 (September 2021): 86-91. doi:10.51441.BioMedica.5-503

Harvard Style

Xueyuan Li, Miao Yu, Miaozhong Li, Kyaw Thura, Xiaoling Zhou, Chen Hong (2021) Prednisone Combined with Antiviral Agents for the Treatment of Early Idiopathic Brachial Plexus Neuritis: Report of 5 Cases. biomedica, 30 (September 2021): 86-91. doi:10.51441.BioMedica.5-503

Turabian Style

Xueyuan Li, Miao Yu, Miaozhong Li, Kyaw Thura, Xiaoling Zhou, Chen Hong. 2021. Prednisone Combined with Antiviral Agents for the Treatment of Early Idiopathic Brachial Plexus Neuritis: Report of 5 Cases. Biomedica, 30 (September 2021): 86-91. doi:10.51441.BioMedica.5-503

Chicago Style

Xueyuan Li, Miao Yu, Miaozhong Li, Kyaw Thura, Xiaoling Zhou, Chen Hong. "Prednisone Combined with Antiviral Agents for the Treatment of Early Idiopathic Brachial Plexus Neuritis: Report of 5 Cases." Biomedica 30 (2021), 86-91. doi:10.51441.BioMedica.5-503

MLA (The Modern Language Association) Style

Xueyuan Li, Miao Yu, Miaozhong Li, Kyaw Thura, Xiaoling Zhou, Chen Hong. "Prednisone Combined with Antiviral Agents for the Treatment of Early Idiopathic Brachial Plexus Neuritis: Report of 5 Cases." Biomedica 30.September 2021 (2021), 86-91. Print. doi:10.51441.BioMedica.5-503

APA (American Psychological Association) Style

Xueyuan Li, Miao Yu, Miaozhong Li, Kyaw Thura, Xiaoling Zhou, Chen Hong (2021) Prednisone Combined with Antiviral Agents for the Treatment of Early Idiopathic Brachial Plexus Neuritis: Report of 5 Cases. Biomedica, 30 (September 2021), 86-91. doi:10.51441.BioMedica.5-503