Background and Objective: It is important to understand the proximity of the inferior alveolar nerve canal (IANC) and lower third molar before performing any surgical procedure. The aim of the study was to determine the proximity of the IANC to the lower third molar and the pattern of impaction among the population of Punjab, Pakistan.Methods: This cross-sectional observational study was conducted from December, 2021 to November, 2022 in the Maxillofacial Surgery departments of four private dental institutes in Punjab. A total of 134 patients were recruited. The IANC proximity and impaction pattern of the lower third molars of both sides were assessed using cone beam computed tomography images. Statistical Package for Social Sciences was used for analysis and a p-value less than or equal to 0.05 was set as significant.Results: There were 76 (56.7%) males and 58 (43.3%) females, with the majority belonging to the age range from 40 to... Continue Reading

Background and Objective: Sirtuin 1 (SIRT1) is nicotinamide adenine dinucleotide-dependent histone deacetylase. It plays a crucial role in the regulation of fat and glucose metabolism by influencing proteins involved in nutrient sensing and energy regulation. This study examined the effects of the interaction between the SIRT1 rs7069102 variant and lifestyle factors on obesity-associated anthropometric and metabolic phenotypes in the local population of Pakistan.Methods: The study population incorporated 612 participants comprising an equal number of individuals having both normal body mass index and those who were overweight/obese. Anthropometric indices were assessed by employing standard protocols of corresponding body measurements while metabolic variables were determined by conducting relevant biochemical assays. The data related to lifestyle factors was collected by developing a standard questionnaire. Genotyping of rs7069102 was done by performing a TaqMan allelic discrimination assay. The data were analyzed by means of Statistical Package for the Social Sciences software by performing regression... Continue Reading

Abstract Objective: The objective of the study was to make a comparison between the frequencies of flare-ups occurring in single versus multiple visit non-surgical root canal therapy in multi-rooted teeth with pulpal necrosis. Materials and Methods: 360 patients with multiple-rooted Non-Vital Teeth between the ages of 20 and 60, from both genders, were selected and randomly assigned into two groups. In group A, patients underwent root canal treatment in single visit. In group B, patients underwent 2 visits for root canal treatment. On follow up, if patient complained of endodontic pain not controlled with medication with or without swelling within 24 to 48 hours postoperatively, then flare-up was noted. Results: The mean age recorded in group A was 41.90 ± 10.94 years whereas in group B, it was 41.21 ± 9.25 years. 148 (41.11%) were male and 212 (58.89%) were female with male to female ratio of 1:1.4. Frequency of... Continue Reading

ABSTRACT Background and Objective: Dental anxiety has been reported to be the fifth most prevalent reason for anxiety among adults. It is a negative psychological effect of the stress-induced, precisely due to dental treatment. This study was conducted to assess the effect of audiovisual aid in reducing dental anxiety during tooth extraction. Methodology: 162 participants who needed tooth extraction were randomly divided into two groups of 81, each using a simple randomization method using the lottery method. Participants in Group A were given verbal information about the procedure preoperatively, while participants in Group B were shown an audiovisual clip. Preoperative and postoperative anxiety levels were self-reported by the patients on the Visual Analogue Scale from 0 to 10. Data were analyzed using SPSS version 25. Results: The mean age of the study participants was 35.69. Among the 162 participants, 43.8% were females, and 56.2% were males. The mean score for... Continue Reading

Background and Objective: Helicobacter pylori (H. Pylori) infection is more common in type 2 diabetic patients (T2DM) than in non-diabetic individuals. Because in diabetes, both cellular and humoral immunity is compromised so that’s why diabetics’ patients are more susceptible to H. pylori infection. Chronic inflammation is a common symptom of H. pylori. To detect and compare H. Pylori IgG antibody in patients with type 2 diabetes mellitus and non-diabetic individuals. Methodology: This case-control study was performed at the pathology lab of Gulab Devi Educational Complex Lahore, Pakistan from August 2022 to January 2023. In this study 100 diabetic patients and 100 control subjects included according to inclusion & exclusion criteria. After taking written consent blood sample was collected from diabetic & non-diabetic individuals and their blood sugar random (BSR) and glycated haemoglobin (HbA1c) was measured. Results: In this study, 63 (63%) of the 200 diabetic individuals tested positive for H.... Continue Reading

Background: Acne vulgaris is a common skin condition caused by excessive sebum production, bacterial colonization, and inflammation. Objective: To determine the effect of the 5% topical zinc sulfate solution on reducing the GAGS score in patients with acne vulgaris. Methodology: This descriptive case series study was conducted in the department of dermatology of a public sector hospital from August 1, 2019, to February 1, 2020. A total of one hundred participants fulfilling the inclusion criteria were enrolled. Pretreatment photographs were taken, and the baseline GAGS score was documented. Each patient was instructed to use 5% topical zinc sulfate twice daily on the affected area for two months. Compliance was assured by follow-up after every 15 days. The participants were followed up for two months to assess the changes in the GAGS score. Results: A total of one hundred participants suffering from acne vulgaris were included. The mean age was 28.6 years.... Continue Reading

Fine-needle aspiration cytology (FNAC) is used as a valuable method for examining suspected salivary gland lesions. It is a simple, costeffective, and minimally invasive procedure with high specificity and sensitivity. Due to the cellular heterogeneity and overlapping architectural features, it can be difficult to distinguish between non-neoplastic processes, benign lesions, and/or malignancies in salivary glands on routine stains. Cell block methods are currently replacing surgical biopsy-based diagnostic methods on the basis of utilizing aspirates from FNAC with a rapid and reliable potential for reaching a conclusive diagnosis. Ancillary investigations including a panel of immunohistochemical markers are frequently applied on cytology specimens in the era of precision diagnostics to offer a specific diagnosis and even prognostic information for optimal patient care. Continue Reading

N/A Continue Reading

N/A Continue Reading