BioMedica |

Original Article

Volume: 36 | Issue: 1 | Published: Mar 31, 2020 | Pages: 53 - 58 | DOI: 10.24911/BioMedica/5-154

Utility of Cell Block in Diagnosis of Serous Effusions in Comparison with Conventional Cytological Smears

Authors: Nosheen Khurram , Imran Yousaf , Noshin Wasim Yusuf

Article Info

Authors

Nosheen Khurram

Department of Pathology, Rashid Latif Medical College, Lahore-Pakistan.

Imran Yousaf

Department of Pathology, Rashid Latif Medical College Lahore-Pakistan.

Noshin Wasim Yusuf

Department of Pathology, Rashid Latif Medical College Lahore-Pakistan.

Publication History

Received: October 21, 2019

Revised: February 20, 2020

Accepted: March 22, 2020

Published: March 31, 2020

Abstract

Background and Objectives: Diagnostic issues arise in everyday practice to reach a conclusive diagnosisafter cytological evaluation of smears. This study was designed to determine the diagnostic accuracy of cell block technique by comparing with conventional cytological smears in cytopathological diagnosis of serous effusions.
Methods: This study of diagnostic accuracy comprising of one hundred clinically and radiologically proven cases of pleural and peritoneal effusions was conducted in the Department of Pathology, Rashid Latif Medical College Lahore over a period of one year (January 2018 to January 2019). Non-probability, purposive sampling technique was used. Diagnostic accuracy of conventional cytological smear and cell block was compared using histopathology as gold standard.
Results: The sensitivity, specificity, positive predictive value and negative predictive value of conventional cytological smear and cell block method was 78.40%, 69.20, 87.90%, 52.90%, and 94.6%, 88.5%, 95.90%, 85.20% respectively. Diagnostic accuracy of cytological smears was 76% as compared to 93% of cell block method.
Conclusion: To reach a conclusive diagnosis for cytological evaluation of effusion, cell block analysis is mandatory step in addition to conventional cytological methods especially in smears that remain suspicious or inconclusive on routine cytology.

Keywords: Serous effusion, Conventional smear, Cell block, Reactive mesothelial cells

Pubmed Style

Nosheen Khurram, Imran Yousaf, Noshin Wasim Yusuf. Utility of Cell Block in Diagnosis of Serous Effusions in Comparison with Conventional Cytological Smears. BioMedica. 2020; 31 (March 2020): 53-58. doi:10.24911/BioMedica/5-154

Web Style

Nosheen Khurram, Imran Yousaf, Noshin Wasim Yusuf. Utility of Cell Block in Diagnosis of Serous Effusions in Comparison with Conventional Cytological Smears. https://biomedicapk.com/articles/154 [Access: December 22, 2024]. doi:10.24911/BioMedica/5-154

AMA (American Medical Association) Style

Vancouver/ICMJE Style

Nosheen Khurram, Imran Yousaf, Noshin Wasim Yusuf. Utility of Cell Block in Diagnosis of Serous Effusions in Comparison with Conventional Cytological Smears. BioMedica. (2020), [cited December 22, 2024]; 31 (March 2020): 53-58. doi:10.24911/BioMedica/5-154

Harvard Style

Nosheen Khurram, Imran Yousaf, Noshin Wasim Yusuf (2020) Utility of Cell Block in Diagnosis of Serous Effusions in Comparison with Conventional Cytological Smears. BioMedica, 31 (March 2020): 53-58. doi:10.24911/BioMedica/5-154

Chicago Style

Nosheen Khurram, Imran Yousaf, Noshin Wasim Yusuf. "Utility of Cell Block in Diagnosis of Serous Effusions in Comparison with Conventional Cytological Smears." 31 (2020), 53-58. doi:10.24911/BioMedica/5-154

MLA (The Modern Language Association) Style

Nosheen Khurram, Imran Yousaf, Noshin Wasim Yusuf. "Utility of Cell Block in Diagnosis of Serous Effusions in Comparison with Conventional Cytological Smears." 31.March 2020 (2020), 53-58. Print. doi:10.24911/BioMedica/5-154

APA (American Psychological Association) Style

Nosheen Khurram, Imran Yousaf, Noshin Wasim Yusuf (2020) Utility of Cell Block in Diagnosis of Serous Effusions in Comparison with Conventional Cytological Smears. , 31 (March 2020), 53-58. doi:10.24911/BioMedica/5-154