BioMedica |

Original Article

Volume: 40 | Issue: 3 | Published: Sep 25, 2024 | Pages: 130 - 134 | DOI: 10.24911/BioMedica/5-1183

The role of probiotic in preventing recurrent urinary tract infections in pregnant women

Authors: Sadia Kazi , Saif Ur Rehman , Sara Jamil Khan , Dr Shuja Anwar Kazi , Saadia Zainab , Shahnaz Bano

Article Info

Authors

Sadia Kazi

Professor, Department of Pharmacology, Isra University, Hyderabad, Pakistan

Saif Ur Rehman

Associate Professor, Department of Physiology, Frontier Medical and Dental College, Abbottabad, Pakistan

Sara Jamil Khan

Assistant Professor, Department of Gynaecology, Frontier Medical and Dental College, Abbottabad, Pakistan

Dr Shuja Anwar Kazi

Assistant Professor, Department of Biomedical Sciences, College of Medicine, King Faisal University, Al Hofuf, Saudi Arabia

Saadia Zainab

Associate Professor, Department of Physiology, Al Nafees Medical College, Islamabad, Pakistan

Shahnaz Bano

Assistant Professor, Department of Pharmacology, Isra University, Hyderabad, Pakistan

Publication History

Received: July 05, 2024

Revised: August 18, 2024

Accepted: September 13, 2024

Published: September 25, 2024

Abstract

Background and Objective: Urinary tract infections (UTIs) are a major public health disease after upper respiratory tract infections, affecting more than 150 million people worldwide The study was aimed to identify the effects of probiotics in preventing recurrent UTIs in pregnant women.

Methods: This randomized controlled trial was conducted on pregnant females (1st and 2nd trimester), aged between 18 and 40 years presenting with UTIs. A total of 60 participants were equally and randomly allocated into two groups, i.e., Group A, who received probiotics along with conventional treatment, and Group B which acted as a control and received the placebo along with the conventional treatment. Urine D-R evaluations were performed pre and post intervention. The pre-post analysis was performed using a paired t-test as the data were normally distributed. To compare analysis among groups, an independent sample t test was applied. p (<0.05) was considered as statistically significant.

Results: Group-A (Probiotic) showed greater improvement among variables where the Leukocyte count improved from 15.2 ± 4.3 (cells/HPF) to 10.5 ± 3.1 (cells/HPF) (p = 0.001), and the level of nitrites improved from 0.8 ± 0.2 to 0.5 ± 0.1μmol/ml (p = 0.02) as compared to Group-B (p = 0.05).

Conclusion: The addition of probiotics in the conventional treatment regimen in pregnant females with recurrent UTIs leads to earlier recovery as depicted by the clinico-pathological assessment.

Keywords: Probiotics, Urinary tract Infection, Urine Detailed Report

Pubmed Style

Sadia Kazi, Saif Ur Rehman, Sara Jamil Khan, Dr Shuja Anwar Kazi, Saadia Zainab, Shahnaz Bano. The role of probiotic in preventing recurrent urinary tract infections in pregnant women. BioMedica. 2024; 25 (September 2024): 130-134. doi:10.24911/BioMedica/5-1183

Web Style

Sadia Kazi, Saif Ur Rehman, Sara Jamil Khan, Dr Shuja Anwar Kazi, Saadia Zainab, Shahnaz Bano. The role of probiotic in preventing recurrent urinary tract infections in pregnant women. https://biomedicapk.com/articles/1183 [Access: March 25, 2025]. doi:10.24911/BioMedica/5-1183

AMA (American Medical Association) Style

Vancouver/ICMJE Style

Sadia Kazi, Saif Ur Rehman, Sara Jamil Khan, Dr Shuja Anwar Kazi, Saadia Zainab, Shahnaz Bano. The role of probiotic in preventing recurrent urinary tract infections in pregnant women. BioMedica. (2024), [cited March 25, 2025]; 25 (September 2024): 130-134. doi:10.24911/BioMedica/5-1183

Harvard Style

Sadia Kazi, Saif Ur Rehman, Sara Jamil Khan, Dr Shuja Anwar Kazi, Saadia Zainab, Shahnaz Bano (2024) The role of probiotic in preventing recurrent urinary tract infections in pregnant women. BioMedica, 25 (September 2024): 130-134. doi:10.24911/BioMedica/5-1183

Chicago Style

Sadia Kazi, Saif Ur Rehman, Sara Jamil Khan, Dr Shuja Anwar Kazi, Saadia Zainab, Shahnaz Bano. "The role of probiotic in preventing recurrent urinary tract infections in pregnant women." 25 (2024), 130-134. doi:10.24911/BioMedica/5-1183

MLA (The Modern Language Association) Style

APA (American Psychological Association) Style

Sadia Kazi, Saif Ur Rehman, Sara Jamil Khan, Dr Shuja Anwar Kazi, Saadia Zainab, Shahnaz Bano (2024) The role of probiotic in preventing recurrent urinary tract infections in pregnant women. , 25 (September 2024), 130-134. doi:10.24911/BioMedica/5-1183