Authors: Asma Saadia , Tahir Naeem , Saad Jamal-ud-Din Alvi , Majid Ali , Toqeer Ali Butt

Abstract

Background and Objective: Platelet transfusion is one of the most crucial therapeutic approaches in medicine. Single Donor Platelets (SDP) are being preferred because of higher platelet count per unit,leukocyte reduction during collection and fewer donor exposures thus reducing the risk of infection and alloimmunization. This study was conducted to compare Haemonetics MCS plus with Baxter CS3000 plus cell separator in terms of processing time, quality of platelet concentrates, donor experience and individual choice.
Methods: Two hundred platelet pheresis procedures performed on Haemonetics MCS plus during a period from January 2018 to August 2019 were compared with the same number of procedures performed using Baxter CS3000 plus cell separator from July 2015 to April 2019.
Results: The mean platelet count of the product was higher with Baxter, 1741.6 ± 347 x 103/μL as
compared to1676 ± 301 x 103/μL with Haemonetics. No significant difference between the two instruments was observed regarding processing time, product volume and yield.
Conclusion: The two instruments are comparable in terms of time, volume and yield of the product but Haemonetics is better because of donors’ comfort and for being operator friendly.

Keywords: Cell separator, Haemonetics MCS plus, Baxter CS3000 plus, Platelet pheresis, Platelet yield.