Review Article
Volume: 36 | Issue: 2S | Published: Jun 24, 2020 | Pages: 125 - 129
Immunological Basis of COVID-19
Authors: Shah Jahan , Romeeza Tahir , Faheem Shahzad , Khursheed Javed , Muhammad Kashif , Nadeem Afzal
Article Info
Authors
Shah Jahan
Associate Professor, Department of Immunology, University of Health Sciences, Lahore – Pakistan.
Romeeza Tahir
Department of Immunology, University of Health Sciences, Lahore – Pakistan.
Faheem Shahzad
Department of Immunology, University of Health Sciences, Lahore – Pakistan.
Khursheed Javed
Department of Immunology, University of Health Sciences, Lahore – Pakistan.
Muhammad Kashif
Department of Immunology, University of Health Sciences, Lahore – Pakistan.
Nadeem Afzal
Department of Immunology, University of Health Sciences, Lahore – Pakistan.
Publication History
Received: May 13, 2020
Revised: May 20, 2020
Accepted: June 19, 2020
Published: June 24, 2020
Abstract
Currently major challenge for scientists is to cope with Coronavirus infection that alters host immune response in different ways. There is variability in immune response in diverse populations against this infection and particularly immunity of a certain population against SARS-CoV-2is not clear. Many factors such as viral and host genetics that play crucial in this infection but immunological aspects are more important in infection and disease progression. Its different patterns of spread and severity needs timely focus to design strategies against this disease. This review sums up the concepts related to host immune response to SARS-CoV-2, cellular and humoral immunity, cytokines storm and immunization against COVID-19.
Keywords: Coronavirus, COVID-19, SARS-CoV-2, Immune response..
