BioMedica |

Original Article

Volume: 40 | Issue: 3 | Published: Sep 25, 2024 | Pages: 139 - 143 | DOI: 10.24911/BioMedica/5-1180

Frequency of neoplastic and non-neoplastic lesions of the thyroid gland in tertiary care Hospitals of Lahore

Authors: Raja Yasser Shahbaz , Natalia Malik , Amna Sohail , Mustafa Qadeer , Faiqua Yasser , Hina Zafar Raja

Article Info

Authors

Raja Yasser Shahbaz

Department of Medicine, Rashid Latif Khan University Medical College, Lahore, Pakistan

Natalia Malik

Resident Prosthodontic Department, Institute of Dentistry, CMH Lahore Medical College, Lahore, Pakistan

Amna Sohail

Department of Oral Biology, Institute of Dentistry, CMH Lahore Medical College, Lahore, Pakistan

Mustafa Qadeer

Department of Oral Biology, Institute of Dentistry, CMH Lahore Medical College, Lahore, Pakistan

Faiqua Yasser

Head of Department of Oral Pathology, Institute of Dentistry, CMH Lahore Medical College, Lahore, Pakistan

Hina Zafar Raja

Head of Prosthodontic Department, Rahbar College of Dentistry, CMH Lahore Medical College, Lahore, Pakistan

Publication History

Received: June 20, 2024

Revised: August 03, 2024

Accepted: September 15, 2024

Published: September 25, 2024

Abstract

Background and Objective: Thyroid lesions stand as the predominant endocrine disorders witnessing a substantial global surge in the incidence over recent decades. This study was designed to assess the frequency of neoplastic and non-neoplastic thyroid lesions, focusing on variations across age groups and genders within two tertiary care hospitals in Lahore, Pakistan.

Methods: This retrospective cross-sectional study was conducted at the Pathology Departments of Combined Military Hospital Lahore and Sheikh Zayed Hospital Lahore from the year 2017 to 2021. Histopathological data of 1,217 patients was assessed, with 333 patients having thyroid lesions. The lesions were classified into neoplastic and non-neoplastic. Statistical analysis was performed using the Chi-square test.

Results: Among the 1,217 patients, 333 (27.3%) were diagnosed with thyroid-related lesions, of which 303 (90.9%) were neoplastic and 30 (9.0%) were non neoplastic. Neoplastic lesions included multinodular goiter (41.4%), adenomatous colloid goiter (32.7%), papillary carcinoma (10.2%), and follicular adenoma (6.6%). Non-neoplastic lesions comprised Hashimoto’s thyroiditis (8.1%) and thyroglossal cysts (0.9%). The frequency of thyroid lesions was significantly higher in males (56.6%) (p = 0.001). There was a statistically significant variation in the distribution of lesion types across different age groups (p < 0.001).

Conclusion: Papillary carcinoma emerged as the sole malignant thyroid lesion identified, highlighting its prominence within the study population. These findings underscore the necessity for region-specific epidemiological research to better understand thyroid pathology and inform targeted screening and management strategies.

Keywords: Thyroid, histopathology, lesions, neoplastic, non-neoplastic.

Pubmed Style

Raja Yasser Shahbaz, Natalia Malik, Amna Sohail, Mustafa Qadeer, Faiqua Yasser, Hina Zafar Raja. Frequency of neoplastic and non-neoplastic lesions of the thyroid gland in tertiary care Hospitals of Lahore. BioMedica. 2024; 25 (September 2024): 139-143. doi:10.24911/BioMedica/5-1180

Web Style

Raja Yasser Shahbaz, Natalia Malik, Amna Sohail, Mustafa Qadeer, Faiqua Yasser, Hina Zafar Raja. Frequency of neoplastic and non-neoplastic lesions of the thyroid gland in tertiary care Hospitals of Lahore. https://biomedicapk.com/articles/1180 [Access: March 25, 2025]. doi:10.24911/BioMedica/5-1180

AMA (American Medical Association) Style

Vancouver/ICMJE Style

Raja Yasser Shahbaz, Natalia Malik, Amna Sohail, Mustafa Qadeer, Faiqua Yasser, Hina Zafar Raja. Frequency of neoplastic and non-neoplastic lesions of the thyroid gland in tertiary care Hospitals of Lahore. BioMedica. (2024), [cited March 25, 2025]; 25 (September 2024): 139-143. doi:10.24911/BioMedica/5-1180

Harvard Style

Raja Yasser Shahbaz, Natalia Malik, Amna Sohail, Mustafa Qadeer, Faiqua Yasser, Hina Zafar Raja (2024) Frequency of neoplastic and non-neoplastic lesions of the thyroid gland in tertiary care Hospitals of Lahore. BioMedica, 25 (September 2024): 139-143. doi:10.24911/BioMedica/5-1180

Chicago Style

Raja Yasser Shahbaz, Natalia Malik, Amna Sohail, Mustafa Qadeer, Faiqua Yasser, Hina Zafar Raja. "Frequency of neoplastic and non-neoplastic lesions of the thyroid gland in tertiary care Hospitals of Lahore." 25 (2024), 139-143. doi:10.24911/BioMedica/5-1180

MLA (The Modern Language Association) Style

APA (American Psychological Association) Style

Raja Yasser Shahbaz, Natalia Malik, Amna Sohail, Mustafa Qadeer, Faiqua Yasser, Hina Zafar Raja (2024) Frequency of neoplastic and non-neoplastic lesions of the thyroid gland in tertiary care Hospitals of Lahore. , 25 (September 2024), 139-143. doi:10.24911/BioMedica/5-1180